Senior Scientist II at Allergan Aesthetics, an AbbVie Company in Irvine, CA, United States

Job description

• The Senior Scientist II will lead the development and site transfer of manufacturing processes for next-generation medical aesthetics products. This role is responsible for designing, planning, executing, documenting, and interpreting scientific experiments in collaboration with a team of scientists and engineers. The position also requires strong cross-functional partnership with internal and external stakeholders, along with excellent communication and presentation skills. The processes and capabilities developed by the Senior Scientist will follow design of experiments principles to support the consistent production of finished products that meet critical quality attributes. This is a high-impact role that directly supports AbbVie’s rapidly growing medical aesthetics portfolio, with a primary focus on dermal fillers.

Responsibilities

• Scale up and develop manufacturing processes of novel medical devices with the goal of improving process robustness and transferability.
• Lead execution of manufacturing processes such as solution preparation, synthesis, purification, sterile filtration, compounding, terminal sterilization and product filling in primary packaging.
• Draft guidance documentation such as work instructions, master batch records, and protocols.
• Analyze experimental data generated by the analytical team, to better understand and also improve process capability where needed.
• Collaborates with global cross functional partners on joint experimental studies to achieve common project goals.
• Prepare and review design of experiments to better understand product critical process parameters and proven acceptable ranges.
• Maintain a high level of productivity in the lab.
• Participates, and presents in project team meetings to propose project activities, review completed tasks, and technical progress as needed.
• Writes, reviews and issues batch records, build packages, reports, memoranda, and other documents for internal and external distribution.
• Generates ROI’s and works closely with corporate patent counsel in generating IP documentation.
• Remains as an internal technical consultant through the entire product development life cycle.
• Transfer manufacturing processes to/from internal and/or external manufacturing sites.
• Searches, reviews, and evaluates current literatures and relevant technology landscape to help maintain and extend internal technical competence.
• Attends and participates in scientific meetings as company’s representative to gain knowledge about new products or technologies pertinent to corporate business interest.
• Communicates and recommends new biomaterial, product, and technology related ideas to supervisor and other research managers to maintain and enhance company’s position in the marketplace.

Requirements

• BS (12+ years industry), MS (10+ years industry) or Ph.D. (4+ years industry) in Biomedical Engineering, Biomaterials Science, Materials Engineering, Bioengineering, Chemical Engineering, or related fields. Preferably with a Ph.D. degree.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Effective writer and communicator of research and regulatory materials.
• Work experience involving medical device and combination products is preferred.

Skills

Required

• Strong cross-functional partnership
• Effective writer and communicator
• Manufacturing process development
• Scale-up
• Solution preparation
• Synthesis
• Purification
• Sterile filtration
• Compounding
• Terminal sterilization
• Product filling
• Design of experiments

Benefits

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our long-term incentive programs.
• Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​
• Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​