Medical Director: Gastroenterology, Pulmonary, Rheumatology, Nephrology at Roche in South San Francisco

Job description

• We advance science so that we all have more time with the people we love.
• The Early Clinical Development (ECD) OMNI group at Genentech drives innovation across a broad portfolio of immunology indications, advancing breakthrough science from First-in-Human studies through Proof-of-Concept and initial pivotal decisions. Driven by gRED’s mission to make fundamental scientific discoveries and help develop them into best-in-class therapeutics that provide unique benefits to patients, our team translates complex biology into transformative therapies.

Responsibilities

• Drive Clinical Trial Design: Author clinical protocols and design early-phase (Phase I/II) studies to establish biologic and clinical proof-of-concept for novel molecular entities (NMEs).
• Serve as Medical Monitor: Provide medical oversight, safety monitoring, and clinical expertise across active trials while collaborating with trial sites, investigators, and CROs.
• Lead Cross-Functional Strategy: Represent Clinical Science on multi-disciplinary Clinical Science Teams (CST) and Protocol Execution Teams (PET), integrating insights across biomarkers, safety, regulatory, and commercial functions.
• Guide Regulatory & Asset Strategy: Author clinical sections for INDs, IBs, and health authority briefing materials, supporting direct interactions with global regulatory bodies (FDA, EMA).
• Engage Global Scientific Leaders: Collaborate with internal research groups, external Key Opinion Leaders (KOLs), and scientific advisory boards to refine disease area strategies and inform portfolio decisions.

Requirements

• Clinical Expertise: M.D. with Board Certification or eligibility in Gastroenterology, Pulmonary, Rheumatology, Nephrology, or a related specialty (M.D./Ph.D. preferred).
• Research Track Record: 2+ years of clinical, translational, or basic research experience within academia or the biopharmaceutical industry, with a demonstrated focus on immunology or inflammation.
• Development Acumen: Thorough understanding of early clinical drug development principles (Phases I–II), trial methodology, GCP/ICH guidelines, and sophisticated clinical data interpretation.
• Strategic & Collaborative Mindset: Adept at synthesizing complex biomarker and safety data to shape asset strategy and influence decisions across cross-functional matrix teams.
• Scientific Communicator: Highly effective communicator capable of building strong collaborative networks with academic investigators, regulatory bodies, and internal research partners.

Skills

Required

• Trial methodology
• GCP/ICH guidelines
• Clinical data interpretation
• Effective communication

Benefits

• The expected salary range for this position based on the primary location of South San Francisco, California is $213,400 - $396,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
• Benefits