Executive/Senior/Medical Science Liaison (MSL) – Field Medical Affairs - Geography - Mid-West at Edgewise Therapeutics in US
- Company: Edgewise Therapeutics
- Location: US
- Posted: Sep 24, 2026
- Type: Full-time
- Salary: MSL - $170,000-$220,000; Sr. MSL - $210,000 - $240,000; Executive - $230,000 - $260,000
- Experience: 4+ years
Overview
At Edgewise, we are focused on advancing novel, muscle-targeted therapeutics for serious cardiovascular and cardiometabolic conditions with significant unmet need. Leveraging our expertise in muscle biology and small molecule drug development, we are building a cardiovascular pipeline that includes …
Job description
- At Edgewise, we are focused on advancing novel, muscle-targeted therapeutics for serious cardiovascular and cardiometabolic conditions with significant unmet need. Leveraging our expertise in muscle biology and small molecule drug development, we are building a cardiovascular pipeline that includes programs for hypertrophic cardiomyopathy, heart failure and other serious cardiovascular diseases.
- We’re building a passionate, experienced team committed to tackling complex scientific and clinical challenges and delivering meaningful outcomes for patients. If you’re looking to do work that matters, we’d love to hear from you.
- We are seeking passionate and driven Medical Science Liaisons (MSLs) to join our growing team at a nimble, innovative pharmaceutical company dedicated to developing therapies for patients with hypertrophic cardiomyopathy (HCM) and heart failure. As an MSL, you will serve as a key scientific resource to key opinion leaders (KOLs) and healthcare professionals (HCPs), helping to bridge cutting-edge science and clinical practice. This position is field-based and requires the ability to engage with thought leaders, clinicians, and researchers in the cardiovascular space. You will play a crucial role in supporting our mission to bring transformative medicines to patients who need them most.
Responsibilities
- Serve as a scientific expert in cardiology, specifically HCM and heart failure, engaging in peer-to-peer discussions with KOLs and HCPs.
- Build and maintain strong relationships with KOLs in academic centers, and community HCPs.
- Provide timely, fair-balanced, and accurate scientific information in response to unsolicited medical inquiries.
- Support medical and clinical teams during clinical trials by assisting in identifying potential sites, assisting with patient recruitment strategies, and facilitating communication between sites and internal teams.
- Provide scientific support for advisory boards, including preparation, facilitation, and follow-up.
- Attend scientific congresses and symposia to gather and disseminate relevant scientific information. Staff medical booth, as needed.
- Deliver scientific presentations internally and externally to support education and training initiatives.
- Collaborate cross-functionally with internal stakeholders (e.g., Clinical Development, Regulatory, Commercial, and Pharmacovigilance) to ensure scientific alignment.
- Gather, document and disseminate medical insights and competitive intelligence to inform company strategy and development programs.
- Effectively manage assigned territory to optimize scientific engagement and operational efficiency.
- Maintain compliance with all applicable laws, regulations, and internal policies.
Requirements
- Accredited doctorate degree in a life-science or basic-science discipline (Pharm.D., D.Sc., D.N.P., Ph.D., or M.D./D.O.) strongly preferred.
- Minimum of 4+ years of experience as an MSL or in a field medical/scientific role within the pharmaceutical or biotech industry.
- Prior experience in cardiology or rare diseases, preferably related to HCM and heart failure
- Demonstrated ability to interact effectively with KOLs and other HCPs in both academic and community settings.
- Understanding of clinical trial design, execution, and the regulatory environment.
- Experience analyzing and communicating complex scientific data in a clear and meaningful way.
- Proven success managing both internal and external stakeholders in a dynamic, matrixed organization.
- Recognized as a valued collaborator and contributor within cross-functional teams.
- Deep scientific knowledge and passion for cardiovascular medicine.
- Excellent communication, presentation, and interpersonal skills.
- Ability to travel up to 60–70% with overnight stays, as needed. May include international travels.
- Self-starter with strong organizational skills and the ability to work independently in a fast-paced, entrepreneurial environment.
- Demonstrated ability to efficiently manage time and priorities, lead projects while valuing input from others, and operate with a high level of integrity, professionalism, and initiative.
- Take and follow directions, accept guidance from management, and adjust quickly to changes
Skills
Required
- Advisory board support
- Delivering scientific presentations
- Cross-functional collaboration
- Territory management
- Compliance with laws and regulations
- Time management and prioritization
- Leadership and project management
Benefits
- Our Benefits: We are proud to offer health benefits, a discretionary bonus plan, stock option grants. a stock purchase plan, a 401(k) with match and paid time off to our team members as part of their compensation plan.
- Sr. MSL - $210,000 - $240,000
- Executive - $230,000 - $260,000